| abstract |
The present invention provides compounds of formula (I), or stereoisomers, tautomers or pharmaceutically acceptable salts thereof, wherein: These compounds are selective inhibitors of factor XIa, or dual inhibitors of fXIa and plasma calicaine. The present invention also relates to pharmaceutical compositions comprising these compounds, and methods of using the same to treat thrombotic and / or inflammatory disorders. (I) In this formula, all variables are as defined herein. |