abstract |
The present invention relates to a vaccine composition comprising a cyclic peptide, an antibody against a cyclic peptide or an anticancer composition comprising the same, wherein the vaccine composition of the present invention exhibits inhibitory activity against cancer metastasis, Binds to the tumor-specific antigen TM4SF5 with a high affinity and significantly inhibits the growth, metastasis and invasion of tumor cells expressing it, and thus can be used for diagnosis, prevention or treatment of various cancers expressing TM4SF5. |