http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101825647-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c9ef4f73964bb0246544be3baa6f780 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_799b6c8cb40ea97102dceda7bfe7b5c7 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2560-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9b66e706976f933d6d77128aa8e7903 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddf546a29c7942bc1df60ef446b688f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f442d9af7ba5adcc3e1e7d751f1dd6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82a487cc80d95b1c16ce7928dc82b76c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f631105939e8e44a6d86735895a16a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a76eb23ab94deef3e8886752b10e0e6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_961295daee91b0b377898d32bea46ecc |
publicationDate | 2018-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101825647-B1 |
titleOfInvention | Cancer marker analysing method by glycan monitoring of glycoprotein through intact molecular weighing |
abstract | Challenge: Protein glycosylation is very sensitive to changes in the internal and external environment, and research is underway to directly use it in various diagnostic systems including cancer. Diagnosis of disease using oligosaccharide is very efficient, but when the oligosaccharide is separated and used for diagnosis, much time and effort are required for sample preparation, mass analysis and data processing, and an undesired artificial composition may be produced. Solution: In order to minimize this, we invented a novel cancer diagnosis analysis method that applies the glycosylated protein as it is to the cancer diagnosis. In the present invention, the disulfide bond of a multifactorial structure was cleaved to divide into alpha and beta chains, and then the total chain length was measured to analyze the sugar chain pattern of the beta chain. It can be used as a quick and accurate diagnostic method in diagnosis of diseases by recognizing the glycosylation pattern of protein through short time of mass analysis time and rapid data processing within 10 minutes after performing minimal pretreatment such as disulfide bond cleavage without separating oligosaccharide . |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102222001-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102222002-B1 |
priorityDate | 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.