http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101820515-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
filingDate | 2015-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101820515-B1 |
titleOfInvention | A composition for preventing or inhibiting a metastasis of a primary thyroid cancer |
abstract | The present invention relates to a pharmaceutical composition for preventing or inhibiting primary thyroid cancer metastasis. The inventors of the present invention have for the first time determined that the deactivation of the Slit-Robo pathway is associated with a bad prognosis of thyroid cancer including large tumor size, lymph node metastasis, distant metastasis and recurrence. Accordingly, the present inventors propose a therapeutic agent capable of inhibiting primary thyroid cancer metastasis using human SLIT2 (Slit homolog 2) protein or gene. The present invention first confirmed the role of the Slit-Robo pathway as a tumor suppressor in thyroid cancer and suggests the possibility of Slit2 as a new biomarker and a new molecular therapy target. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20230047879-A |
priorityDate | 2015-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 760.