http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101818943-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73616276d1ec7cb8db7c1c8cf2c045db http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1774566419837559f8c5d33897cc5993 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-308 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 |
| filingDate | 2017-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c104489a98de02d183b749893044d03a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d60254acaca1178073d3a7141fe13af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b1a3234f3428ce90c54152d0055ff84 |
| publicationDate | 2018-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101818943-B1 |
| titleOfInvention | Composition for prevention, improvement or treatment of breast cancer comprising bepridil as an active ingredient |
| abstract | The present invention relates to a composition for preventing, ameliorating or treating breast cancer, which comprises bepridil as an active ingredient. More specifically, the present invention relates to a composition comprising bepridil or a pharmaceutically acceptable salt thereof as an active ingredient, To inhibit the growth of breast cancer cells, and to decrease the expression of c-Myc, KLF5, and DRD2 in breast cancer cells, thereby effectively preventing, ameliorating, or treating breast cancer by inducing transfection and activation, promoting apoptosis of breast cancer cells, Compositions and food compositions. The composition of the present invention induces nuclear migration and activation of FOXO3 in breast cancer cells, promotes apoptosis of breast cancer cells, inhibits the growth of breast cancer cells, decreases the expression of c-Myc, KLF5 and DRD2 in breast cancer cells Breast cancer can be effectively prevented, improved or treated. In particular, the composition of the present invention is specifically classified among breast cancers, and it is possible to effectively prevent, ameliorate, or treat triple negative breast cancer having a high mortality rate because there is no effective treatment yet. |
| priorityDate | 2017-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 445.