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filingDate 2016-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101816119-B1
titleOfInvention miR-30a as a marker for diagnosing of anti-cancer drug resistance and composition for overcoming anti-cancer drug resistance comprising it's inhibitor
abstract The present invention relates to a pharmaceutical composition for inhibiting resistance to an anticancer agent comprising, as an active ingredient, an inhibitor of miR-30a and miR-30a as an anti-cancer drug resistance diagnostic marker. Specifically, the expression of miR-30a is increased in cancer- 30a by inhibiting the expression of miR-30a or inhibiting the binding of miR-307 to miR-217 by using a method of providing information necessary for diagnosing cancer resistance of cancer patients and containing an inhibitor of miR-30a as an active ingredient And to a pharmaceutical composition exhibiting an effect of suppressing tolerance to the disease. According to the present invention, the method for measuring the expression level of miR-30a can effectively provide information on the resistance of a cancer patient to an anticancer agent, and can provide a pharmaceutical composition according to the present invention containing an inhibitor of miR-30a When used, the resistance to such anticancer agents can be effectively inhibited. In addition, an anticancer drug resistance inhibitor can be effectively screened by screening for a substance capable of inhibiting the expression of miR-30a.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019245135-A1
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priorityDate 2016-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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