| abstract |
Compounds of formula (I) and all possible stereoisomers thereof; Or a pharmaceutically acceptable salt or solvate thereof; Pharmaceutical preparations; Use of compound (I) as an HCV inhibitor is disclosed: In this formula, R 4 is monophosphate, diphosphate or triphosphate ester; expression Lt; / RTI > R 7 is optionally substituted phenyl; Optionally substituted naphthyl; Or an optionally substituted indolyl; R 8 and R 8 ' are hydrogen, C 1 -C 6 alkyl, benzyl, or phenyl; R 8 and R 8 'taken together with the carbon atom to which they are attached form C 3 -C 7 cycloalkyl; R 9 is C 1 -C 10 alkyl, C 3 -C 7 cycloalkyl, phenyl or phenyl-C 1 -C 6 alkyl, wherein the phenyl moiety of the phenyl or phenyl-C 1 -C 6 alkyl is optionally substituted. |