Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26c3152b36ac46f5d8d7508eea9928ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e99f37e09d46c79ed0aa6e08aa260e0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-4953 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 |
filingDate |
2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ea40ecb8bd02d9270965a8933fe6f90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05d67afbf6bbc0ae7fd6ac14f4b937ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2795ea03fdad54b2b94c24d066a357c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86d5118cb3cf26342cb9ade7f28b3c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ee32be4d0ea98af3cd44a2f037dbd1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_888247fd469c92cf19af434f931aaea5 |
publicationDate |
2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101793013-B1 |
titleOfInvention |
Composition for treating or preventing neurodegenerative disease containing extract of fumitremorgin b |
abstract |
The present invention relates to an anti-inflammatory composition comprising pseudomorphine B isolated from SF-5497, an anoceanic marine bacterium-derived fungus, as an active ingredient. Since the composition of the present invention shows excellent anti-inflammatory effect in mouse brain cells , A pharmaceutical composition and a cosmetic composition for prevention, improvement and treatment of brain inflammation-related diseases. Specifically, the pseudomorphine B derived from the natural product has no cytotoxicity and safety has been recognized, and as a result of experiments using mouse microglia, it has been found that hematin The present invention has been found to be effective in increasing the expression and activity of Heme Oxygenase-1 (HO-1) and inhibiting cellular inflammatory reaction. Thus, the anti-inflammatory composition comprising the anti- An anti-inflammatory agent for suppressing inflammation and a cosmetic composition having anti-inflammatory effect. |
priorityDate |
2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |