http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101791770-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101791770-B1 |
| titleOfInvention | Method for producing protein |
| abstract | Although high-efficiency protein synthesis was thought to be highly effective in promoting polyosome formation with multiple ribosomes attached to mRNA, the mechanism of promoting the formation of polysomes of p180 protein was not clear. The inventors of the present application newly found a SF3b4 protein as a protein that specifically interacts with the coiled-coil domain, which is responsible for the function of promoting the formation of polysomes of the p180 protein, and a protein that promotes ER (ER) localization of mRNA , And localization of the mRNA on the endoplasmic reticulum is markedly elevated in cells highly expressing both the ER protein localization promoting proteins (for example, SF3b4 protein) and the p180 protein, It is possible to raise the secretory function of the cells. In addition, by inserting a specific nucleotide sequence into the expression plasmid, the SF3b4 protein having the protein expression enhancing effect can be locally localized on the endoplasmic reticulum membrane and the mRNA in the polysomes can be heavily shifted. Through this, it is possible to increase the secretory ability of the cells Appeared. |
| priorityDate | 2013-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 880.