abstract |
The present invention relates to an expression cassette comprising a gene related to Alzheimer's disease, a vector, and a transformed cell line using the same. More specifically, the expression cassette of the present invention is used for APP (amyloid precursor protein), Tau (tau protein) And PS1 (presenilin 1: Preseniline-1) mutant gene can be simultaneously expressed. The present invention also relates to a cell line transformed with an expression cassette or vector containing the genes, and further to an animal model transformed with the vector or cell line. |