http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101789417-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0668 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0665 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
filingDate | 2016-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101789417-B1 |
titleOfInvention | Direct conversion method of mesenchymal stromal stem cells to endothelial cells by defined transcription factors |
abstract | The present invention relates to a method for transforming mesenchymal stem cells into endothelial cells using specific transcription factors, and more particularly to a method for transforming mesenchymal stem cells into endothelial cells using specific transcription factors Oct4, Nanog, Tall and LMO2 . According to the present invention, among the reprogramming factors of the cell, two kinds of genes that are not directly related to cancer induction and transcription factors related to vascular development are selected and classified into two types of transcription factors that are not expressed in the mesenchymal stem cells The present inventors have developed a method of converting mesenchymal stem cells, which are adult cells or adult stem cells, into endothelial cells by combining these four, and this method is applied to the production of endothelial cells for constituting regenerated tissues in tissue engineering and treatment of ischemic diseases There is an effect that can be. |
priorityDate | 2015-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 646.