http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101771222-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 |
filingDate | 2015-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101771222-B1 |
titleOfInvention | Pharmaceutical composition for prevention or treatment of inflammatory diseases containing integrin inhibitor as an active ingredient |
abstract | The present invention relates to a pharmaceutical composition for the prophylaxis and treatment of an inflammatory disease comprising an integrin inhibitor and more particularly to an inhibitory activity against the integrin α5β1 inhibitor of the compound represented by the formula As a result, Compounds 1 to 60 according to the present invention have an excellent effect of blocking integrin activity by inhibiting the conversion of? 5? 1 into an active form through binding of? 5? 1 with an inhibitor before binding of? 5? 1 with fibronectin A pharmaceutical composition containing as an active ingredient a low molecular compound and a derivative thereof that inhibits the binding of integrin [alpha] 5 [beta] l of the present invention to fibronectin as an extracellular matrix protein can be effectively used for the prevention and treatment of inflammatory diseases . |
priorityDate | 2015-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.