http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101770584-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D245-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D245-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 |
| filingDate | 2010-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101770584-B1 |
| titleOfInvention | Novel conjugates, preparation thereof, and therapeutic use thereof |
| abstract | The present invention relates to a targeting agent of formula (I) to which at least one cryptopequine is attached: (I) Wherein R 1 represents a halogen atom, R 2 represents an OH group, an acyl group derived from an amino acid AA or a (C 1 -C 4 ) alkanoyloxy group; Or alternatively R 1 and R 2 form an epoxy unit; AA represents a natural or artificial amino acid; R 3 is a (C 1 -C 6 ) alkyl group; R 4 and R 5 are both H or together form a double bond CH = CH between C13 and C14; R 6 and R 7 are, independently of each other, H or a group (C 1 -C 6 ) alkyl; R 8 and R 9 are independently of each other H or a (C 1 -C 6 ) alkyl group; R 10 is H, OH group, (C 1 -C 4) alkoxy, halogen or NH 2, NH (C 1 -C 6) alkyl or N (C 1 -C 6) at least one of the phenyl nucleus selected from alkyl groups Lt; / RTI > R 11 is at least one substituent of the phenyl nucleus selected from H or (C 1 -C 4 ) alkyl groups; The targeting agent and the cryptopyrin derivative are covalently bonded and the bond is located at the ortho (o), meta (m) or para (p) position of the phenyl nucleus containing the CR 1 unit. |
| priorityDate | 2009-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 338.