http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101770494-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate | 2014-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101770494-B1 |
| titleOfInvention | 2-phenylimidazo[1,2-a]pyrimidines as imaging agents |
| abstract | The present invention relates to compounds of formula (I), or pharmaceutically acceptable acid addition salts thereof, racemic mixtures or the corresponding enantiomers and / or optical isomers thereof. The compounds are suitable as imaging tools to improve diagnosis by identifying potential patients with excess tau aggregates in the brain in which Alzheimer ' s disease develops: (I) In this formula, R 1 is 3 H, halogen, lower alkyl, di-methyl-amino, NHC (O) - lower alkyl, C (O) O- lower alkyl, lower alkoxy, OC (3 H) 3, O 11 CH 3, OCH 2 CH 2 18 F, lower alkoxy substituted with halogen, hydroxy, lower alkyl substituted by hydroxy, and S-lower alkyl, or by a heterocyclyl group Lt; / RTI > 2,3-dihydrobenzo [b] [1,4] dioxin-6-yl, or indolin-2- Heteroaryl selected from the group consisting of thiophenyl, benzofuranyl, benzothiophenyl, pyrazinyl, and benzothiazolyl; R < 2 > is hydrogen, lower alkyl or lower alkyl substituted by halogen, R 3 is lower alkyl, C ( 3 H) 3 , 11 CH 3 , lower alkyl substituted by halogen, - (CH 2 ) 2 -O-lower alkyl, or cycloalkyl substituted by halogen; R 2 and R 3 together with the N atom to which they are attached form -CH 2 CH 2 CHRCH 2 CH 2 -, -CH 2 CH 2 CH 2 CH 2 -, -CH 2 CH 2 CH 2 -, -CH 2 CH 2 -NR-CH 2 CH 2 -, -CH 2 CH 2 -O-CH 2 CH 2 -, -CH 2 CH 2 CHRCH 2 -, -CH 2 CHRCH 2 - or ≪ / RTI > R is hydrogen, halogen, lower alkyl substituted by halogen, or lower alkoxy. |
| priorityDate | 2013-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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