| abstract |
The present invention relates to a cyclohexene derivative, a process for its preparation, and a pharmaceutical composition for the prevention or treatment of metabolic diseases containing the same as an active ingredient. The cyclohexene derivative according to the present invention comprises GPR-119 (G protein-coupled receptor 119) (Glucagon-like peptide-1), which is a neuroendocrine protein, is induced by activating cAMP (cyclic adenosine monophosphate), and weight loss and hypoglycemic effect are simultaneously exhibited. Thus, obesity, I Useful as a pharmaceutical composition for the prevention or treatment of metabolic diseases such as type 2 diabetes, type 2 diabetes, unsuitable endometriosis, insulin resistance syndrome, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia, syndrome X Can be used. |