http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101754076-B1

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filingDate 2015-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101754076-B1
titleOfInvention Method and kit for genotyping HLA-DRB1 and HLA-DRB3/4/5 using real-time PCR
abstract The present invention can provide each combination of primers and probes in a one-to-one correspondence manner that specifically amplifies and detects the HLA-DRB3 / 4/5 gene of each HLA-DRB1 gene, -DRB1 and HLA-DRB3 / 4/5 genotyping analysis is simple and clear, so that HLA-DRB1 and HLA-DRB3 / 4/5 genotyping analysis for a large amount of samples can be performed easily and accurately in a short time Time PCR analysis method and kit capable of effectively judging, at a genetic level, the suitability of individuals for identification and / or tissue transplantation at the time of forensic investigation. According to the present invention, HLA-DRB3 / 4/5 genotyping analysis as well as HLA-DRB1 can be performed simultaneously, rapidly, accurately, and quantitatively with high specificity and sensitivity from samples to be analyzed using real-time PCR Therefore, HLA-DRB1 and HLA-DRB3 / 4/5 genotyping can be performed reliably and efficiently in the personal identification of forensic investigations and in determining the suitability of tissue transplantation during surgery. In particular, according to the present invention, HLA-DRB1 and HLA-DRB3 / 4/5 genotyping can be performed directly and clearly without any comparison of complex analysis tables, -DRB1 and HLA-DRB3 / 4/5 genotype analysis can be performed effectively at the genetic level.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102040282-B1
priorityDate 2015-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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