abstract |
There is provided a compound that selectively modulates the sphingosine 1 phosphate receptor, comprising a compound that modulates subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. The use, treatment or prevention methods and methods of manufacture of the compositions of the present invention, including the compounds of the present invention, are provided in connection with the treatment or prevention of diseases, conditions and disorders in which the modulation of sphingosine 1 phosphate receptors is medically recommended . |