http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101744033-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C57-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C55-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 |
| filingDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101744033-B1 |
| titleOfInvention | Nitrogen-containing heterocyclic compound salt or crystal thereof, pharmaceutical composition, and flt3 inhibitor |
| abstract | A compound having excellent stability and / or solubility, and more excellent FLT3 inhibitory activity, and a pharmaceutical composition. The present invention relates to a process for the preparation of (S, E) -N- (1 - ((5- (2- ((4-cyanophenyl) amino) -4- (propylamino) pyrimidin- Yl) amino) -1-oxopropane-2-yl) -4- (dimethylamino) -N-methylbut-2-enamide (Compound A). These salts or crystals thereof have excellent FLT3 inhibitory activity and are also useful for treatment of diseases or conditions related to FLT3 because of their excellent storage stability or solubility and other physical properties as pharmaceuticals. The present invention also provides pharmaceutical compositions and FLT3 inhibitors containing these salts or crystals thereof. |
| priorityDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 175.