http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101739601-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1114 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| filingDate | 2012-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101739601-B1 |
| titleOfInvention | Novel Use of TanshinoneIIA for inhibition of functional plasticity of regulatory T cells |
| abstract | The present invention relates to a novel use of a Tanshinone IIA compound for inhibiting the differentiation of regulatory T cells (Tregs), and more particularly, to Th17 cells of regulatory T cells (Tregs) containing Tanshinone IIA compound as an active ingredient ; The present invention relates to a composition for the prevention or treatment of immune diseases containing Tanshin IIA compound and regulatory T cells (Treg) as an active ingredient, and to a method for producing regulatory T cells (Treg) in which immunosuppression is maintained using Tanshinone IIA compounds. The tanshinone IIA compound according to the present invention has a new use for effectively maintaining and enhancing the function as regulatory T cells (Treg) through the activity of inhibiting the differentiation plasticity of regulatory T cells (Treg) into Th17 cells , It is possible to block the differentiation of regulatory T cells (Tregs) into Th17 cells even in a pathological environment when they are used in combination with regulatory T cells (Treg), thereby providing a therapeutic agent for more effective treatment of immune diseases . |
| priorityDate | 2012-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 139.