| abstract |
The present invention is a toxic factor that is a surface exposed protein (Protein E: pE), which can be detected in Haemophilus influenza and comprises an amino acid sequence of SEQ ID NO: 1, an immunogenic fragment of the surface exposed protein, and a recombinant immunogenic protein (pE (A)) or a surface exposed protein with its truncated variants based on the surface exposed protein. Nucleic acid sequences, vaccines, plasmids and phages, extrinsic hosts, recombinant nucleic acid sequences, fusion proteins or fusion products are also described. Methods of producing the protein or truncated fragment thereof by recombination are also described. |