http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101734926-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-48 |
| filingDate | 2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101734926-B1 |
| titleOfInvention | Pharmaceutical composition comprising the root extract of pachyrhizus erosus an effective component for prevention or treatment of thrombotic disorders and health functional food comprising the same |
| abstract | The present invention relates to a pharmaceutical composition and a health functional food for preventing or treating / improving thrombotic disorders containing an underground part extract of Pachyrhizus erosus as an active ingredient. More particularly, The present invention relates to a pharmaceutical composition and a health functional food for prevention or treatment / improvement of a thrombotic disease which contains, as an active ingredient, a hot water or ethanol extract of tuberous root and a fraction obtained as a sequential solvent fraction of the above extract. The pharmaceutical compositions for the prevention or treatment / improvement of the thrombotic diseases of the present invention and the extract of yamvin as an active ingredient of the health functional food can be obtained by extracting the yamvin root mass with hot water or ethanol And fractions obtained by successively fractionating the extract with hexane, ethyl acetate and butanol. The above-mentioned active ingredients are prepared by using enzymes (thrombin and prothrombin) related to thrombus formation and strong And exhibits antithrombotic activity and has an excellent effect that can be used for prevention and treatment of thrombotic diseases such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation due to inhibition of platelet aggregation. In particular, the yamvin extract and the active fraction of the present invention have excellent thermal stability and do not exhibit the inhibition of blood coagulation factor inhibition, thrombogenesis-related enzyme inhibition and platelet aggregation inhibition effect in an acidic condition of pH 2 and in plasma, It is an extremely useful invention in the pharmaceutical industry and the food industry because it has excellent hemolytic activity and can be prepared in various forms such as extract, powder, ring, and tablet and can be prepared at any time. |
| priorityDate | 2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.