http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101732609-B1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1629 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate | 2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101732609-B1 |
titleOfInvention | Polymer formulation to control sequential release of bioactive agents |
abstract | The present invention relates to a polymer blend preparation in which a biodegradable polymer microparticle loaded with a physiologically active substance is mixed with a polymer gel matrix in which a physiologically active substance is dispersed, wherein each of the physiologically active substances is sequentially released from the polymer blend preparation Polymer mixed preparation. The polymer mixed preparation according to the present invention is in a sol state outside the body, and after the injection into the body, the polymer mixed preparation is gelated or solidified to stably maintain the initially injected volume, and the polymeric gel matrix is prepared from the solidified polymer mixed preparation The dispersed physiologically active substance is released at the initial stage of infusion to more fundamentally treat the vocal cord dysfunction (voice / swallowing disorder) (vocal smooth muscle reconstruction), and at the same time, the biodegradable polymer microparticles The physiologically active substance can be released in a sustained release form, effectively regenerating the damaged tissue around the vocal cords (vocal mucosa / unique layer reconstruction), and can be effectively used for the treatment of various vocal fold diseases. |
priorityDate | 2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 171.