| abstract |
The present invention relates to a composition for inhibiting breast cancer stem cell growth, a fragrance composition, a pharmaceutical composition for inhibiting metastasis of breast cancer, or treating or preventing breast cancer, comprising phenylacetaldehyde or a pharmaceutically acceptable salt thereof as an active ingredient A food composition, and the like. The phenylacetaldehyde of the present invention inhibits the growth of breast cancer cells and inhibits the formation of breast cancer stem cells. In addition, it inhibited the expression of self-regenerating genes such as Nanog, Sox2, Oct4, and CD44, which are known to be expressed in mammalian stem cells, and that the production of IL-6, which is known to be involved in mammalian pair formation in breast cancer stem cells And inhibited the STAT3 signaling pathway. Accordingly, the compound inhibits the growth of breast cancer stem cells and can be used for the treatment of breast cancer. |