| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd192e7c8283a1f8284e90d2b967091a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2250-208
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-322 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-06 |
| filingDate |
2016-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea1a71017f8b83a0c5251794f34f0523
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e299cbe5eef42bb38e3921ff73e1c663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_699f94ad54ca5c89e0b1b98eb9000b9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef5b1d253a5b7a6bb276ed791bcfc4ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c71ea645c77514efd513b155b0641e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1666d8dd355de2146b6dedeef379e9c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e631e4d9fe52238fdc73333aa2cd95f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad68c19037c8780a0caf983017170a79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_258726a1b00440d3787aaa437f3b1d93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc89f778f28eb8245038a6cb124b0582 |
| publicationDate |
2017-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-101723869-B1 |
| titleOfInvention |
Pharmaceutical Composition for Preventing or Treating Inflammatory Diseases Comprising Dihydroisocoumarin Derivatives |
| abstract |
The present invention relates to a pharmaceutical composition for preventing or treating an inflammatory disease containing a dihydroisoxaparin derivative as an active ingredient, and more particularly, to a pharmaceutical composition for preventing or treating inflammatory diseases comprising a marine fungus Aspergillus sp. SF-5974 and SF-5976 as an active ingredient. The present invention also relates to a pharmaceutical composition for preventing or treating inflammatory diseases, which comprises a dihydroiso-coumarin derivative having an anti-inflammatory effect, The pharmaceutical composition for the prevention or treatment of an inflammatory disease comprising the dihydroisoquamarin derivative according to the present invention as an active ingredient is useful for the production of nitric oxide (NO) and prostaglandin E2 (PGE 2 ) in microglia (INOS) and cyclooxygenase-2 (COX-2), inhibiting IκB-α phosphorylation and NF-κB activity, and reducing the level of p38 MARK phosphorylation And since it is free from cytotoxicity, it can be usefully used as a pharmaceutical composition for preventing or treating inflammatory diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107400108-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107400108-A |
| priorityDate |
2016-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |