http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101699567-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2012-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101699567-B1 |
| titleOfInvention | A composition for preventing or treating an immunological disease comprising an expression or activity inhibitor of JunB as an active ingredient |
| abstract | The present invention relates to a composition for preventing or treating an immunological disease comprising an expression or activity inhibitor of JunB as an active ingredient. More particularly, the present invention relates to a composition for preventing or treating an immunosuppression, comprising an antisense nucleotide complementary to mRNA of JunB gene, interfering RNA, short hairpin RNA, and an antibody against JunB protein, and a method for preventing or treating immune diseases using the same. . According to the present invention, inhibition of the expression or activity of JunB inhibits the differentiation of Th17 cells causing immune diseases, inhibits the production of inflammatory cytokine IL-17, inhibits inflammatory autoantibodies, The activity of inhibiting the proliferation of immune cells is excellent and can be widely used for the production of a therapeutic agent for treating various immune diseases caused by immunomodulation abnormality. |
| priorityDate | 2012-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 315.