| abstract |
The present invention relates to a composition for preventing or treating diabetes or obesity comprising apelin-12, apelin-16 or apelin-36 as an active ingredient. More particularly, the resent invention relates to a composition for preventing or treating diabetes or obesity comprising apelin-12, apelin-16 or apelin-36 which stimulates secretion of insulin caused by a high concentration of sugar. According to the present invention, apelin-12, apelin-16 or apelin-36 shows not only the effects of reducing blood cholesterol, triglyceride levels and blood sugar through the stimulation of secretion of insulin but also excellent anti-diabetic and anti-obesity effects, including inhibition of fat accumulation, fatty liver and kidney damages, and thus is useful as an agent for preventing or treating diabetes, diabetes complications or obesity. |