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filingDate 2016-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c50f4367272be9c37e69a5c2bcccc09
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publicationDate 2016-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101680786-B1
titleOfInvention Bone regeneration biomaterials and for manufacturing method thereof
abstract The biomaterial for bone regeneration according to the present invention and the method for producing the biomaterial for bone regeneration and the method for producing the same are capable of activating osteoblasts and killing osteoclasts using a biocompatible polymer material excellent in blood compatibility and cell tissue compatibility with natural bone and having the same structural or chemical composition And can inhibit bone loss and osteoporosis, and is potentially useful for the development of a drug delivery system as well as osteoporosis, and is used as a therapeutic agent for various bone diseases, thereby exhibiting a bone regeneration effect. In addition, the biomaterial for bone regeneration of the present invention and the method for producing the biomaterial for bone regeneration not only activate the osteoblast cell temporarily but also promote the interaction between the biomaterial and the bone tissue, do not exhibit cytotoxicity, The activity of osteoclasts can be controlled. In addition, it is possible to prevent the agglomeration of nanoparticles and to disperse evenly while maintaining the original particle size, so that excellent osteoblast proliferation promoting effect can be expected and excellent bone regeneration effect is exhibited. Therefore, instead of the existing artificial bone substitute, It can be very useful as a material.
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