| abstract |
The present invention provides a substituted amide of formula (I), which is useful as an active ingredient of a medicinal composition, particularly a medicinal composition for the treatment of a disease caused by lysophosphatidic acid (LPA). A represents an aromatic 5-membered heterocyclic group which may be substituted, B represents an aromatic 5-membered heterocyclic group which may be substituted, X represents a single bond or - (CR X1 R X2 ) n -, n represents 1, 2, 3 or 4, R X1 and R X2 are hydrogen, Y 1 to Y 5 are CR Y or N, R Y is hydrogen, R 1 and R 2 are hydrogen, and m is 1, 2 or 3, , R 3 represents hydrogen or the like, R 4 represents lower alkyl which may be substituted, etc.) |