http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101677970-B1

Outgoing Links

Predicate Object
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D337-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D337-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-38
filingDate 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101677970-B1
titleOfInvention Process for producing zaltoprofen and its derivatives
abstract The present invention relates to a method for producing zaltoprofen or a maltoprofen derivative by a cyclization reaction in the form of a Friedel-Crafts reaction type, wherein 6.5 times Or less of polyphosphoric acid is used as a condensing agent so that impurities such as a detectable amount of a dimer are not produced at a purity sufficient for use as a pharmaceutically active ingredient, The present invention relates to a process for preparing zaltoprofen or zaltoprofen derivatives on a simple, economical and industrial scale. Specifically, in the presence of at least one organic solvent selected from the group consisting of 1,1,2-trichloroethane, methylcyclohexane, cyclohexane, n-heptane, etc., the raw material for pulmonary exchange is intramolecularly cyclized To a process for producing zaltoprofen or a maltoprofen derivative by ring closure by a reaction.
priorityDate 2012-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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