http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101677970-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D337-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D337-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-38 |
filingDate | 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101677970-B1 |
titleOfInvention | Process for producing zaltoprofen and its derivatives |
abstract | The present invention relates to a method for producing zaltoprofen or a maltoprofen derivative by a cyclization reaction in the form of a Friedel-Crafts reaction type, wherein 6.5 times Or less of polyphosphoric acid is used as a condensing agent so that impurities such as a detectable amount of a dimer are not produced at a purity sufficient for use as a pharmaceutically active ingredient, The present invention relates to a process for preparing zaltoprofen or zaltoprofen derivatives on a simple, economical and industrial scale. Specifically, in the presence of at least one organic solvent selected from the group consisting of 1,1,2-trichloroethane, methylcyclohexane, cyclohexane, n-heptane, etc., the raw material for pulmonary exchange is intramolecularly cyclized To a process for producing zaltoprofen or a maltoprofen derivative by ring closure by a reaction. |
priorityDate | 2012-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.