http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101676158-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 |
| filingDate | 2015-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101676158-B1 |
| titleOfInvention | A novel 6-amino-5-(substituted)pyrimidine-2,4(1H,3H)-dione derivatives, a method for preparing the same and use thereof |
| abstract | The present invention relates to a novel 6-amino-5- (substituted) pyrimidine-2,4 (1H, 3H) -dione derivative or a pharmaceutically acceptable salt thereof, a process for preparing the same, A pharmaceutical composition for preventing or treating osteogenic differentiation, and a composition for inducing bone differentiation of stem cells. Since the pharmaceutical composition comprising the 6-amino-5-substituted pyrimidine-2,4 (1H, 3H) -dione derivative according to the present invention promotes osteoblast differentiation and mineralization to promote osteogenesis, And can be usefully used as a prophylactic and therapeutic agent for bone diseases including osteoporosis. In addition, since the BMP-2 pathway can be activated, bone differentiation of the stem cells induced thereby can be promoted. |
| priorityDate | 2015-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 168.