Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 |
filingDate |
2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2016-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101673728-B1 |
titleOfInvention |
Inhibitors of bruton's tyrosine kinase |
abstract |
Disclosed herein are compounds according to formula (I) that inhibit Btk: Formula I Wherein the variables are as defined herein. The compounds disclosed herein are useful for modulating the activity of Btk and for treating diseases associated with excessive Btk activity. In addition, the compounds are useful for treating inflammatory and autoimmune diseases associated with abnormal B cell proliferation, such as rheumatoid arthritis. Also disclosed are compositions comprising a compound of formula I and at least one carrier, diluent or excipient. |
priorityDate |
2011-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |