http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101672870-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-76 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
| filingDate | 2014-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101672870-B1 |
| titleOfInvention | Novel Cell Line for Evaluating Endoplasmic Reticulum Stress, Composition Comprising the Same, and Uses Thereof |
| abstract | The present invention relates to a novel cell line for measuring ER (endoplasmic reticulum) stress, a composition comprising the same, and uses thereof. More particularly, the present invention provides a cell line transformed with a first recombinant viral vector and a second recombinant viral vector, wherein the first recombinant vector comprises an ER stress response element (ERSE) promoter; And a reporter gene-coding nucleotide sequence operatively linked to the sequence; The second recombinant vector may be a CMV (cytomegalo virus) promoter; And a reporter gene-coding nucleotide sequence operatively linked to the sequence. In addition, the present invention provides a composition for measuring the amount of ER stress expression, a composition for screening toxic substances, a method for producing the cell line, and a method for screening a hepatotoxic inducer. |
| priorityDate | 2014-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.