Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
2009-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2016-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101672563-B1 |
titleOfInvention |
Methods for treating eye disorders |
abstract |
The invention includes non-invasively applying an eyebrow composition comprising a therapeutically effective amount of at least one siRNA that down-regulates the expression of a target gene in association with loss of retinal ganglion cells to the eye surface of the subject, The present invention relates to a composition and a method for inhibiting the loss of retinal ganglion cells in a subject and inhibiting loss of retinal ganglion cells in a subject. The methods of the invention also relate to the use of chemically probed siRNA compounds with structural motifs that down-regulate the expression of human genes expressed in retinal tissues of the eye of mammals. |
priorityDate |
2008-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |