http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101668413-B1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
filingDate 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101668413-B1
titleOfInvention Temperature-responsive molecular syringe and the preparation of the same
abstract The present invention relates to a self-assembly of cinnamoyl polymeric β cyclodextrin (CinPβCD) and Cinnamoyl Pluronic F127 (CinPlu), which is self-aggregated by intermolecular hydrophobic interaction, As the nick chain is hydrophobicized and hydrophobic interactions with the cavities of the beta cyclodextrin moiety, the drug encapsulated in the cavities of the beta cyclodextrin moiety may be released. Accordingly, the self-assembly of the present invention functions as a thermo-responsive molecular syringe, in which the thermally hydrophobic pluronic chain serves as a piston and the cavity of a beta cyclodextrin residue serves as a cylinder.
priorityDate 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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