| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2008-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-101661946-B1 |
| titleOfInvention |
Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
| abstract |
Aspects of the present invention include methods and compositions useful in vaccination strategies that can neutralize Hla to provide immunoprotection against S. aureus pneumonia. In a particular aspect, the invention includes a reduced toxicity Hla, designated as a recombinant mutant form of Hla (HlaH35L), in which histidine 35 is converted to leucine, which eliminates the productive assembly of toxins and inhibits the expression of the test substance from Staphylococcus pneumoniae . |
| priorityDate |
2007-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |