http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101650414-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61C5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-898 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61C5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 |
| filingDate | 2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101650414-B1 |
| titleOfInvention | Manufacturing method of dental-bone filler including crosslinked hyaluronic acid |
| abstract | The present invention relates to a dental bone filling material comprising a cross-linked hyaluronic acid, which is capable of gradually degrading the crosslinked hyaluronic acid until the end of bone synthesis by using a crosslinking technique, filler), comprising: a first step of preparing a sodium hydroxide solution; A second step of mixing and stirring a predetermined amount of sodium hyaluronate with the sodium hydroxide solution prepared above; A third step of adding a BDDE crosslinking agent to the mixed solution prepared in the second step and stirring the mixed solution; A fourth step of subjecting the sodium hyaluronate gel material produced through the third step to a cross-linking reaction; A fifth step of performing the first dialysis of the crosslinked sodium hyaluronate gel through a predetermined sodium chloride solution through the fourth step; A sixth step of performing a second dialysis of the first dialyzed sodium hyaluronate gel through the predetermined dialysis PBS solution through the fifth step; A seventh step of mixing the predetermined PBS solution to the dialyzed sodium hyaluronate gel through the sixth step at a predetermined ratio, finely pulverizing and removing the bubbles; An eighth step of mixing a BMP (Bone Morphology Protein) raw material with the prepared hyaluronic acid sodium gel through the seventh step to prepare a dental bone filling material; A ninth step of filling the prefilled syringe with the dental bone filler manufactured through the eighth step; And a tenth step of subjecting the pre-field syringe filled with the hyaluronic acid sodium gel dental bone filling material produced in the ninth step to autoclaving sterilization at a high pressure. |
| priorityDate | 2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.