| abstract |
The present invention relates to a novel urea derivative, more particularly to a novel urea derivative having the activity of inhibiting histone deacetylase (HDAC), an isomer thereof, a pharmaceutically acceptable salt thereof, a use thereof for producing a medicament, A pharmaceutical composition containing them, a therapeutic method using the composition, and a method for producing a novel urea derivative. The novel selective histone deacetylase (HDAC) inhibitor Urea Derivatives for HDAC Inhibitor according to the present invention is useful as a histone acetylating enzyme mediator of malignant tumors, inflammatory diseases, rheumatoid arthritis, It is effective for diseases. |