http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101643295-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-409 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101643295-B1 |
| titleOfInvention | Water soluble photosensitizer with polysilsesquioxane core and preparation method thereof |
| abstract | The present invention relates to a photosensitizing agent for water-soluble photodynamic diagnosis and treatment and a method for preparing the same. More specifically, the present invention relates to a water-soluble polymer TEG dendron and a material capable of absorbing light such as porphyrin (POSS), a photosensitizer for water-soluble photodynamic diagnosis or treatment containing the polymer, and a process for producing the same. According to the present invention, the incorporation of a triethylene glycol dendron into a porphyrin photosensitizer improves the dispersion of the TEG dendron-porphyrin complex in water compared to conventional photosensitizers, Porphyrins prepared by binding to a POSO core can densify TEG dendron-porphyrin bonds by the number of silicon (Si) of POSS, so that the red-shift is absorbed by the interaction of porphyrins with longer wavelengths. And has the advantage of absorbing light over a wider wavelength range. In addition, Porphyrin, which is concentrated in a PBS solvent similar to the in vivo environment, absorbs light and is rendered soluble in PBS (including water) solvent by TEG dendron, thereby effectively producing active oxygen in vivo . This characteristic is commonly held as a light absorbing material, and can be used as a photo-conversion material and a bio-imaging material. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019066392-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11124660-B2 |
| priorityDate | 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.