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filingDate 2011-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101642903-B1
titleOfInvention Preparation of hydrophilic material coated iron oxide nanoparticles and magnetic resonance contrast agent using thereof
abstract The present invention relates to a method for preparing biocompatible iron oxide nanoparticles by coating iron oxide nanoparticles having improved magnetic properties by a heat treatment using a salt with a hydrophilic substance and a magnetic resonance imaging (MRI) contrast agent . Among the hydrophilic substances, Carboxymethyl dextran (CM-dextran) is most effective for stabilizing iron oxide nanoparticles heat-treated and exhibiting a contrast effect.
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