abstract |
The present invention relates to buprenorphine analog compounds of formula (I), (IA) or (IB) given below. The compounds of the present invention are useful for the treatment of pain, constipation and other conditions that are controlled by the activity of opioids and ORL-1 receptors. (I) ≪ EMI ID = (IB) Wherein R 1 , R 2 , R 8 , R 3a , R 3b , G, X, Z and Y are as defined herein. |