abstract |
The present invention relates to a first human binding domain capable of binding to an epitope of a primate CD3 epsilon chain other than a human and a chimpanzee and a second human binding domain capable of binding EGFR, Her2 / neu or IgE of a non-human and / Domain, and also relates to a method for producing the above-mentioned polypeptide. The invention further relates to host cells comprising vectors and vectors comprising nucleic acids encoding the polypeptides, and the like. In another aspect, the invention provides pharmaceutical compositions comprising said polypeptides and methods of medical use of said polypeptides.n n n Polypeptides, binding domains, nucleic acids, vectors, host cells |