| abstract |
The present invention relates to a pH-responsive cyclodextrin derivative, a process for preparing the same, and a pH-responsive conjugate of the cyclodextrin derivative and a drug, and more particularly to a novel pH-responsive combination of a cyclodextrin or a derivative thereof and a maleic anhydride derivative A pH-responsive cyclodextrin derivative in which a maleic anhydride derivative residue is bonded to a terminal functional group such as NH 2 , N 3 or amino acid of a primary hydroxyl group or cyclodextrin derivative of cyclodextrin as a cyclodextrin derivative, And a pH-responsive conjugate of the cyclodextrin derivative and the drug. |