http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101620087-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate | 2014-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101620087-B1 |
| titleOfInvention | An Antibody Specific for Phosphorylated Phospholipase C-Gamma 2 Protien and Use Thereof |
| abstract | The present invention relates to a phosphorylated PLC [gamma] 2 protein, more particularly an antibody or an antigen binding fragment thereof to Y759 phosphorylated PLC [gamma] 2 protein. The antibody of the present invention may be produced as an sFv or Fab antibody due to complete identification of the antigen binding site or may be provided as a whole humanized antibody by recombining with a constant region derived from a human. Since the antibody of the present invention has a specific binding value to the phosphorylated PLCγ2 protein, it can be usefully used in combination with other antibodies having different binding affinities to control the inhibition rate of PLCγ2 protein phosphorylated in vivo . In addition, the antibody of the present invention can be useful for diagnosis, treatment and prevention of diseases mediated by intracellular signaling by phosphorylation of PLCγ2 protein, including prostate cancer. |
| priorityDate | 2014-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 338.