| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa5d97928d5c303b11f7bb2aeb6377ad |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-539
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1758
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06af228ca0db72f6c2c05adcc01622a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a19d600774812804dfe956a5c512c78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_830efd78fac3b89a46f36ebad1c0eff1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3db1c1f483daab938ef57a1fbf7beb3 |
| publicationDate |
2016-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-101619337-B1 |
| titleOfInvention |
Method for screening agent against cancer metastasis using C-terminal region of p21 |
| abstract |
The present invention provides a method of treating a candidate substance expected to inhibit cancer metastasis to cancer cells and measuring the content of a complex composed of p53, p21, Mdm2 and Slug formed through the C-terminal region of p21 in the cancer cell And a polypeptide of the C-terminal region of p53 or p21 involved in the formation of the complex, and to a pharmaceutical composition for suppressing cancer metastasis. By using the screening method of the cancer metastasis inhibitor provided by the present invention, it is possible to find a preparation that can prevent the cancer metastasis by promoting the degradation of the slug expressed in the cancer cells and suppressing the invasion of the cancer, It can be widely used for the development of more effective cancer therapeutic agents. |
| priorityDate |
2014-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |