http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101617863-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1758 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
| filingDate | 2013-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101617863-B1 |
| titleOfInvention | self-assembled nanostructure having Stabilized alpha-helical that can inhibit tumor and method for preparing the thereof |
| abstract | The present invention relates to a self-assembled nanostructure comprising a stabilized multiple alpha-helical structure, which is excellent in thermal stability and resistance to proteolytic enzymes, and can not be easily degraded in vivo. In addition, the alpha-helical fragment of the nanostructure contains an amino acid sequence derived from the p53 protein, thereby inhibiting the interaction between p53 and MDM2, thereby exhibiting a tumor suppressing effect. Such self-assembled nanostructures will contribute significantly to biotechnological and medical research related to proteins and are expected to be highly applicable as useful therapeutic agents and inhibitors. |
| priorityDate | 2013-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.