http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101617472-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 |
filingDate | 2008-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101617472-B1 |
titleOfInvention | Method of synthesis of morpholino oligomers |
abstract | There is provided a morpholino compound of formula (I) Formula I In Formula I, R 1 is selected from the group consisting of lower alkyl, di (lower alkyl) amino and phenyl; R 2 is selected from the group consisting of lower alkyl, monocyclic arylmethyl, and monocyclic (aryloxy) methyl; R 3 is selected from the group consisting of triaryl methyl and hydrogen; Y is a protected or unprotected hydroxyl or amino group; A chlorophosphoramidate group; And a phosphorodiamidate bonded to the ring nitrogen of an additional morpholino compound or a morpholino oligomer. The compounds include double protected morpholino guanine (MoG) monomers. Also described is the use of this in the synthesis of the morpholino oligomers and the further improved synthesis process of the morpholino oligomers with respect to the deprotection of the protected morpholino ring nitrogen in each monomer coupling step. |
priorityDate | 2007-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 169.