http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101608539-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D279-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 |
filingDate | 2010-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101608539-B1 |
titleOfInvention | Process for the preparation of cephem compounds |
abstract | It is an object of the present invention to provide a method for selectively and high-yielding a Z-form of a cephem compound useful as a synthetic intermediate of a cephalosporin antibiotic substance. According to the present invention, there is provided a process for the preparation of a compound of formula (I), which comprises reacting 3 - [(triphenylphosphoranylidene) methyl] -3- , And a mixture of chlorinated hydrocarbons and lower alcohols in a volume ratio (former: 10: 1 or less) at + 5 ° C to -50 ° C to obtain 3- [2- (4-methylthia Sol-5-yl) vinyl] -3-cephem compound (A). In the following formulas, R 1 and R 2 represent an aromatic hydrocarbon group. |
priorityDate | 2010-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.