abstract |
The compound represented by the formula (I) or a salt thereof has an excellent CRF receptor antagonistic action and also has sufficient pharmacological activity, safety and body kinetics as a medicament. Wherein R 1 represents a group of the formula -A 11 -A 12 ; R 2 means a tetrahydrofurylmethyl group, a tetrahydropyranylmethyl group or a tetrahydropyranyl group; A 11 represents a single bond, a methylene group or a 1,2-ethylene group; A 12 means a C 1-6 alkyl group, a C 3-6 cycloalkyl group or a C 3-6 cycloalkyl group having a methyl group; R 3 represents a methoxy group, a cyano group, a cyclobutyloxymethyl group, a methoxymethyl group or an ethoxymethyl group; R 4 represents a methoxy group or a chlorine atom. |