http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101590959-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-525 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19 |
filingDate | 2014-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101590959-B1 |
titleOfInvention | Recombinant TRAIL Fusion Protein Linked to Hexamerization Domain and Composition for Treating Restenosis Comprising the Same Protein |
abstract | The present invention relates to a TRAIL fusion protein in which a tumor-forming domain is bound to a TRAIL protein, a nucleic acid molecule encoding the same, a recombinant vector comprising the nucleic acid molecule, and a therapeutic and preventive use of the fusion protein or the recombinant vector for vascular restenosis. The TRAIL fusion protein of the present invention is easily inducible to be massaged, has an excellent cell death inducing activity as compared with the TRAIL protein having no plasma protein-forming domain, inhibits the proliferation of endothelial cells induced by vascular injury stimulation, And has the effect of removing endothelial cells. The TRAIL fusion protein of the present invention can be developed as a therapeutic and prophylactic agent for vascular restenosis. |
priorityDate | 2014-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 561.