abstract |
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof. The compounds of formula I below have been found to act as glucagon antagonists or inverse agonists. In conclusion, the compounds of formula I and their pharmaceutical compositions are useful for the treatment of diseases, disorders or conditions mediated by glucagon: Formula I In this formula, R 1 , R 2 , R 3 , A 1 , A 2 , A 3 , A 4 , L, B 1 , B 2 , B 3 and B 4 are as defined herein. |